Quick answer: Rejuran downtime is short for most people. Small raised bumps at injection points usually flatten within one to three days, redness fades within hours to a day, and tiny bruises may last a few days. Most people can return to work the next day, and light makeup is usually fine after about 24 hours.
Key takeaways
- Small bumps are the most common sign and usually settle within one to three days.
- Redness often fades within a day.
- Small bruises can appear and last a few days.
- Machine-assisted injection may leave more even, smaller marks.
- Gentle aftercare helps the skin recover quickly.
What is Rejuran?
Rejuran is a skin booster made by PharmaResearch in Korea. Its main ingredient is polynucleotide (PN), purified DNA fragments from salmon, which support the skin's natural repair process. Rejuran is injected in many small points across the skin to improve texture, fine lines, pores and overall skin quality. There are several versions, including Rejuran Healer, Rejuran i for the eye area, Rejuran S for scars and Rejuran HB with added hyaluronic acid.
Why does Rejuran cause bumps?
Rejuran is placed in the upper skin layers in small amounts. Each injection creates a small raised bump, a little like a mosquito bite, where the product sits before it spreads and absorbs. This is expected and shows the product is placed at the right depth. As the product spreads, the bumps flatten.
Rejuran downtime day by day
- Right after treatment: visible small bumps across the treated area, with redness.
- Day 1: bumps start to soften; redness usually fades.
- Days 2 to 3: most bumps have flattened; skin may feel slightly dry.
- Days 3 to 7: any small bruises fade; skin often looks brighter.
- Weeks 2 to 4: improvements in texture and glow become noticeable.
Does the injection method affect downtime?
Yes. Manual injection with a needle creates distinct bumps at each point, which may be more visible for a day or two. Machine-assisted injection delivers smaller, more even amounts, which some people find leaves fewer visible bumps. Rejuran HB, which contains a local anaesthetic, is often chosen for comfort, while Rejuran S for scars may cause slightly more redness in treated scars.
Does downtime differ by treatment area?
Yes. Under-eye treatment with Rejuran i uses smaller amounts in thin skin, so bumps are small but bruising may be a little more noticeable. Full-face treatment covers a larger area, so bumps are more widespread but usually settle at the same pace. Neck treatment may show slightly longer redness in some people. Your doctor will explain what to expect for each area you choose.
How to reduce Rejuran downtime
- Avoid makeup for about 24 hours to keep injection points clean.
- Avoid saunas, hot baths, intense exercise and alcohol for a day or two.
- Do not press, rub or massage the bumps.
- Use a gentle cleanser and a calming moisturiser.
- Apply sunscreen daily, especially when outdoors.
- Pause strong actives such as retinoids or exfoliating acids for a few days.
When can you wear makeup after Rejuran?
Most doctors suggest waiting about 24 hours before applying makeup. This allows tiny injection points to close and reduces the risk of irritation. Use clean brushes and gentle products when you start again.
Can you plan Rejuran before an event?
Yes, but give yourself a few days. If you have an important event, photos or a video call, plan Rejuran at least three to five days before, so bumps and any bruises have settled. Many people schedule it at the start of a trip to Seoul for this reason.
What is not normal?
Contact your clinic if you notice bumps that become larger, hard, painful or red after a few days, signs of infection such as warmth or discharge, or an allergic reaction. These are uncommon, but your doctor should check them.
Rejuran for visitors
Korea treated about 2.01 million foreign patients in 2025, and around 63% came for dermatology, according to the Ministry of Health and Welfare. Rejuran is one of the most popular skin boosters among visitors. Because downtime is short, it fits into most trips, and you can usually fly home the next day.
Frequently asked questions
How long do Rejuran bumps last?
Usually one to three days.
Can I go to work the day after Rejuran?
Yes. Most people return to work the next day.
Does Rejuran leave bruises?
Small bruises can happen and usually fade within a few days.
Can I fly after Rejuran?
Yes. Most visitors can fly the next day.
Sources
- Ministry of Health and Welfare, Republic of Korea – 2025 foreign patient statistics (press release, 2026).
- Ministry of Food and Drug Safety, Republic of Korea – medical device approval information.
- PharmaResearch – Rejuran product information.
This article is for general information only and is not medical advice. Results vary between individuals. Please consult a qualified physician before any treatment.
