Quick answer: Rejuran Healer is a Korean skin booster made from purified salmon DNA (polynucleotides, or PN). Small injections across the face help repair the skin, improve texture and support elasticity. It stings, so numbing cream is used. You may see small bumps for one to two days, and most people do two to three sessions.
Key takeaways
- Rejuran Healer is a polynucleotide (PN) skin booster developed in Korea.
- It helps skin texture, fine lines, dullness and early loss of firmness.
- It is mildly painful; numbing cream makes it manageable.
- Small bumps usually settle in one to two days, so downtime is short.
- Best results come from a course of two to three sessions.
What is Rejuran Healer?
Rejuran Healer is an injectable skin booster made by PharmaResearch, a Korean company. Its main ingredient is PN (polynucleotide), a material purified from salmon DNA. PN is thought to support the skin's natural repair process, so the skin becomes smoother, calmer and more elastic over time.
Rejuran is one of the most requested skin treatments among visitors to Korea. Korea treated about 2.01 million foreign patients in 2025, and around 63% came for dermatology, according to the Ministry of Health and Welfare. See all of our skin glow treatments.
What are the benefits of Rejuran Healer?
- Smoother texture: skin feels finer and more even.
- Better elasticity: skin looks firmer and more bouncy.
- Fine lines: small lines can soften over a few weeks.
- Calmer skin: it can help sensitive or stressed skin recover.
- Glow: many people notice brighter, healthier-looking skin.
Rejuran does not add volume like a filler and does not lift like HIFU. It improves the quality of the skin itself. Learn the difference in our guide to lip and dermal filler options and our skin boosters page.
Who is Rejuran Healer good for?
- People with dull, tired or rough skin.
- People with fine lines or early loss of firmness.
- People with sensitive skin who want gentle repair.
- People who want better skin with little downtime during a trip.
It is also a good option to combine with lifting. For example, many patients add it after Ultherapy Prime to improve skin quality as well as lift.
Does Rejuran Healer hurt?
Yes, a little. Rejuran is known as one of the more stinging skin boosters, because the liquid is thicker and many small injections are used. Most people describe it as sharp pricks with some stinging.
- Numbing cream is applied for about 30 to 40 minutes before treatment.
- Some clinics use a device injector to make it faster and more even.
- The injection part itself usually takes about 15 to 20 minutes.
If you are worried about pain, tell the doctor. The technique and numbing can be adjusted.
What happens during treatment?
- Consultation: the doctor checks your skin and decides which areas to treat.
- Cleansing and numbing: your face is cleaned and numbing cream is applied.
- Injections: small amounts are injected across the treatment area.
- Soothing care: a calming mask or cooling may be used at the end.
What is the recovery like?
- Day 0–1: small bumps (like tiny mosquito bites) and some redness.
- Day 1–2: most bumps go down. Small bruises are possible.
- Day 3–7: skin usually looks normal and starts to feel smoother.
For the first day, avoid make-up, saunas, alcohol and hard exercise. Do not rub or massage the face. Use gentle skincare and sunscreen. Read our full guide to forehead wrinkle treatments for more on fine-line care.
How many sessions do I need?
Most doctors suggest two to three sessions, two to four weeks apart. After that, many people repeat it every few months to keep the results. If you only have a short trip, one session still helps, and you can continue at home or on your next visit. See how to plan around your stay in our same-day skin treatment guide.
Rejuran Healer vs Rejuran Eye vs Rejuran S
- Rejuran Healer: for the whole face.
- Rejuran Eye: a lighter version for the thin skin around the eyes. See treatments for crow's feet and eye wrinkles.
- Rejuran S: used in small amounts for acne scars and depressed scars.
How to choose a clinic for Rejuran
- Ask to see the sealed, genuine product before treatment.
- Ask how many syringes are planned and get a written quote.
- Check that a doctor performs or supervises the injections.
- Make sure aftercare instructions are given in English.
Our guide to choosing a dermatology clinic in Gangnam explains more.
Frequently asked questions
When will I see results from Rejuran Healer?
Some people see a glow within a week. Texture and firmness usually improve more over three to four weeks.
Can I fly after Rejuran Healer?
Yes. You can usually fly the next day. Small bumps are not a problem for flying.
Is Rejuran made from real salmon?
Its PN is purified from salmon DNA. Tell your doctor if you have a fish allergy.
Can I combine Rejuran with other treatments?
Yes. It is often combined with lasers or lifting. See Korean skin treatments for first-time visitors.
Sources
- Ministry of Health and Welfare, Republic of Korea – 2025 foreign patient statistics (press release, 2026). mohw.go.kr
- PharmaResearch – Rejuran product information. pharmaresearch.co.kr
This article is for general information only and is not medical advice. Results vary between individuals. Please consult a qualified physician before any treatment.
